Episodes

What does it mean to build the future of Bio & Health at the frontier, and why is Austin the place to do it? Recorded live at Health Supernova, this episode explores the deep structural shifts underway in bio, health, and tec...

Is Bitcoin just a financial instrument, or is it a wedge into the future of energy, policy, and power? Brian Morgenstern, head of public policy at Riot Platforms, lays out how mining is becoming critical infrastructure and wh...

Specificity isn’t just a design choice. It’s the differentiator when inches matter. Nick Tippmann, founding partner of TipTop VC, explains how vertical AI is rewriting the software industry by going deeper, not wider. From th...

Innovation does not scale on size alone. It accelerates on the connective threads of an ecosystem, from curated founder groups to open networks and through shared stories and honest champions. Brian Hall, incoming President o...

The $6 trillion chemical industry is on the verge of a revolution as biology moves from the doctor's office to the industrial zone. Veronica Breckenridge, Founder and Managing Partner of First Bight Ventures, is investing in ...

At a hinge point when tech leadership determines the balance of geopolitical power, deep tech investment has never been more critical to America's future. Jordan Blashek, co-founder of America's Frontier Fund , brings his per...

From cutting-edge chips to AI networks the disruption happening up and down the tech stack is upending invention and value. Everything is on the table. Tyson Tuttle , former CEO of Silicon Labs and current founder and CEO of ...

The Texas innovation ecosystem is accelerating at breakneck speed as technologies like AI and institutions such as the Texas Stock Exchange reshape what is possible. Samantha Lewis, Partner at Mercury Fund, recently relocated...

Technology is advancing rapidly, but our social systems and institutions struggle to keep pace. Janine Leger co-founded Edge City, a society incubator accelerating social innovation through popup and experimental communities,...

A unicorn biopharma that ignores the traditional playbook, breaks development speed records, and chose Austin over the traditional biotech hubs. Mallory Factor, Founder and CEO of IntraBio, joins us to share how his Oxford-b...

A coffee conversation turned into a deep exploration and personal obsession about how we shape our world and how it shapes us. I had to invite my partner in that conversation, Dr. Gena Gorlin, on to the podcast to bring her p...

Last June, SXSW announced they would no longer allow military and defense companies as sponsors. This sparked strong reactions from Austin's defense tech community, with one of those reactions leading to the creation of Austi...

This past November, the University of Austin hosted their Inaugural SOMA Summit to explore the amazing transformation in space right now, especially how the commercial space era is decentralizing access. I had the privilege t...

AI is becoming the biggest force multiplier for human talent in history. Austen Allred shares how Gauntlet AI is reimagining engineering education for this new reality and why Austin's is the perfect place to build this ambit...

Space is becoming our next great innovation frontier as we move from 700 astronauts spending days or months to tens of thousands spending years. What does that do to the human body? What does it mean for our species? Eliah Ov...

Austin is rapidly emerging as a significant edtech hub, attracting not just innovative startups but also established industry leaders. In this episode, Udemy's Chief Revenue Officer Rob Rosenthal joins me to explore what skil...

Recorded live at Austin's Quantonation Day this past September, I sat down with senior leaders from Strangeworks, Qunnect, Pasqal, and Tau Systems to discuss the state of quantum and physics tech. This candid panel went beyon...

Optimizing health is about more than just new tech, it's about new models, new ways to engage, and being fun. Jim Donnelly, founder and CEO of Humanaut Health, is pioneering a comprehensive approach that combines advanced dia...

Building companies that can 10x humanity requires extraordinary leadership. Craig Cummings of Moonshots Capital has made finding and backing these leaders his mission. Craig shares his insights on building the next generation...

Nothing motivates a parent to action like a sick child, and for the Andrews family, words like no and impossible became mere roadblocks on their journey to help their kids. Our guests, Pam and Chris Andrews, founders of the F...

Angel investors are supposed to descend and bring early grace to startups but the reality of angel investing is much more complicated and complex. From individual big-check writers to small investors to organized groups, the ...

Are we overlooking the most powerful model of intelligence we have in our race to create smarter machines, the human mind? Peter Voss, CEO and Chief Scientist of Aigo.ai, coined the term "Artificial General Intelligence" (...

What connects the Startup Nation to the Lone Star State? We're witnessing a growing nexus that crosses tech, cultures, and economic verticals. To explore this emerging relationship, I'm joined by Tal Shmueli and Simone Ledeen...

From wargaming to Riskgaming, what can simulations and stories teach us about the future of technology and innovation? Danny Crichton, Head of Editorial and Risk Gaming at Lux Capital, brings his unique insights from his expe...